PUBLICATIONS

Wrestling with Stress

Cells are constantly grappling with stress. We are interested in the roles protein sumoylation plays in stress responses, especially at the transcriptional level.

Oeser, M.L., Amen, T., Nadel, C.M., Bradley, A.I., Reed, B.J., Jones, R.D., Gopalan, J., Kaganovich, D., and R.G. Gardner. 2016.

Dynamic Sumoylation of a Conserved Transcription Corepressor Prevents Persistent Inclusion Formation during Hyperosmotic Stress.

PLOS Genetics 12:1005809

 

Abstract

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More to come.

 

RESEARCH

A conserved deubiquitinating enzyme uses intrinsic disordered regions to scaffold multiple protein-interaction sites. JBC 290: 20601-20612.

Dynamic sumoylation of a conserved transcription corepressor prevents persistent inclusion formation during hyperosmotic stress. PLoS Genetics 12: e1005809.

OUR FUNDING

© 2020  Gardner Lab. All Rights Reserved

Richard Gardner

Department of Pharmacology

Box 357280

University of Washington

Seattle, WA 98195-7280